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  • Chlorhexidine + ketoconazole topical is used to treat superficial skin infections or overgrowth in dogs and cats. When given as directed, side effects are rarely noted, but could include skin irritation. If you suspect an overdose or accidental ingestion, call your veterinary office immediately.

  • Chlorhexidine topical (brand names Chlorhex®, Novalsan®, ChlorhexiDerm®) is an antiseptic used to treat skin infections. It is used to treat surface bacterial and/or fungal skin infections in cats and dogs. This medication may be part of a combination product that includes other medications. Chlorhexidine topical comes in shampoo, liquid, ointment, and wipe form.

  • Chlorhexidine/hydrocortisone/trizEDTA topical (TrizCHLOR® 4HC) is a shampoo and spray conditioner used topically in cats, dogs, and horses to support animals with conditions such as superficial, itchy, bacterial and fungal skin infections (pyoderma); acute moist dermatitis (hotspots); and pododermatitis (skin infections of the foot).

  • Chlorhexidine/ketoconazole/TrizEDTA flush: otic (Mal-A-Ket® Plus) is a liquid antibacterial and antifungal solution used for topical treatment of localized bacterial and yeast infections in dogs and cats. The solution can be used specifically in the ears as a flush treatment.

  • Chlorhexidine/ketoconazole/TrizEDTA flush: topical (Mal-A-Ket® Plus) is a liquid antibacterial and antifungal solution used to manage localized bacterial and yeast infections in dogs and cats. It should only be used topically on the skin or in the ears.

  • Chlorothiazide/hydrochlorothiazide is given by mouth or injection and is used off label to treat nephrogenic diabetes insipidus, high blood pressure, fluid retention, and certain electrolyte imbalances. Give as directed by your veterinarian. Common side effects include electrolyte imbalances, increased need to urinate, vomiting, or diarrhea. Do not use in pets that are allergic to them or sulfa drugs, in lactating pets, or in pets that are not able to make urine. If a negative reaction occurs, please call your veterinary office.

  • Chlorpheniramine maleate is given by mouth and is used off label to treat allergic conditions or as a mild sedative. Common side effects include sleepiness, although other side effects are possible. Do not use in pets that are allergic to it or other similar antihistamines, or pets that are undergoing allergy testing within 2 weeks. If a negative reaction occurs, please call your veterinary office.

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses greater than four months old.

  • Chocolate is toxic to dogs. While rarely fatal, chocolate ingestion often results in significant illness. Chocolate is toxic because it contains the alkaloid theobromine. Theobromine is like caffeine and is used medicinally as a diuretic, heart stimulant, blood vessel dilator, and muscle relaxant.

  • Cholecalciferol (vitamin D3) has become increasingly more common as a residential rodenticide. While it may seem like a safer option than anticoagulants, there is no antidote available and the amount in a single block is a severe overdose in nearly all animals. This handout discusses clinical signs, treatments, and prognosis for cholecalciferol poisoning in pets.